Thimerosal Content in Some US Licensed Vaccines

updated 02-21-2002 (see correction)

http://www.vaccinesafety.edu/thi-table.htm

Vaccine

Brand Name

(click on name for pagkage insert)

Manufacturer

Thimerosal Concentration1

Mercury
 ug/0.5 ml

Date Approved

or Changed

pg in 2002 PDR

Anthrax

Anthrax vaccine

BioPort Corporation

0

0

 

 

DTaP Acel-Imune Wyeth-Ayerst .01% 25 no longer produced 1851
  Tripedia  Aventis Pasteur * --* 03-28-00 817
  Certiva Baxter .01% 25 07-29-98 – no longer produced

 

Infanrix

GlaxoSmithKline

0

0

01-29-97

1562

DTwP

All Products

  

.01%

25

  

 

DT

All Products

  

.01%

25

  

 

Td

All Products

  

.01%

25

  

 

TT

All Products

  

.01%

25

  

 

DTwP-Hib

Tetramune

Wyeth-Ayerst

.01%

25

no longer produced

 

Hib

ActHIB/OmniHib

Aventis Pasteur

0

0

09-27-96

798

  ProHIBiT Aventis Pasteur .01% 25 no longer produced
  TriHIBit Aventis Pasteur * *   817
  HibTITER   multi-dose
                single dose
Wyeth-Ayerst
Wyeth-Ayerst
.01%
0
25
0
  1859
  PedvaxHIB liquid(2) Merck 0 0 03-98 (web) 2148
  COMVAX(3) Merck 0 0 10-02-96 2056

Hepatitis A

Havrix

GlaxoSmithKline

0

0

 

1544

  Vaqta adult/pediatric Merck 0 0 03-29-96 2199

Hepatitis B

Engerix-B preservative free

GlaxoSmithKline

 

*

*

03-28-00

1517

  Engerix-B  GlaxoSmithKline .005% 12.5 no longer produced
  Recombivax HB preservative free Merck 0 0 08-27-99 2178
  Recombivax HB  Merck .005% 12.5  

Hep A-B

Twinrix

GlaxoSmithKline

0

0

05-11-2001

1674 

Influenza

All products in U.S.

  

.01%

25

  

 

IPV

IPOL

Aventis Pasteur

0

0

  

809

Lyme

LYMErix 

GlaxoSmithKline

0

0

12-21-98

1592

Meningococcal

MENOMUNE-A/C/Y/W-135

Aventis Pasteur

*

*

  

813

MMR

M-M-R II 

Merck

0

0

  

2118

Measles

Attenuvax

Merck

0

0

  

2044

OPV

ORIMUNE

Wyeth-Ayerst

0

0

no longer produced

 

Pneumococcal

Prevnar

Wyeth-Ayerst

0

0

02-17-00

1870

  Pnu-mune 23  Wyeth-Ayerst .01% 25   1868
  Pneumovax 23   Merck 0 0 1986 2156

Rabies

 

Rabies Vaccine Adsorbed

Bioport Corporation

.01%

25

03-18-88

  RabAvert Chiron 0 0 10-20-97 1203
 

IMOVAX

Aventis Pasteur 0 0 07-91 (PDR) 807

Rotavirus

Rotashield

Wyeth-Ayerst

0

0

08-31-98

withdrawn 10-15-99

Typhoid

Vivotef Berna

Berna

0

0

04-97 (PDR)

997

Typhoid Fever

Typhim Vi

Aventis Pasteur

0

0

06-95 (PDR)

825

  Typhoid vaccine Wyeth-Ayerst 0 0 02-09-94 (PDR)

Varicella

Varivax

Merck

0

0

03-17-95

2202

Yellow Fever

YF-VAX

Aventis Pasteur

0

0

05-96 (PDR)

827

___ - shaded text indicates vaccines no longer in production

1.    A concentration of 1:10,000 is equivalent to a 0.01% concentration. Thimerosal is approximately 50% Hg by weight.    A 1:10,000 concentration contains 25 micrograms of Hg per 0.5 mL.
2. A previously marketed lyophilized preparation contained 0.005% thimerosal. (*Prior to 02-04-02 this web page incorrectly referenced PedvaxHIB liquid as having contained 0.05% thimerosal.)
3. COMVAX is not approved for use under 6 weeks of age because of decreased response to the Hib component.

* This product should be considered equivalent to thimerosal-free products.  This vaccine may contain trace amounts (<0.3 mcg) of mercury left after post-production thimerosal removal; these amounts have no biological effect.   JAMA 1999;282(18) and JAMA 2000;283(16).

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