Infant mortality rates regressed against number of vaccine doses routinely given
Infant mortality rates
regressed against number of vaccine doses routinely given: is there a
biochemical or synergistic toxicity?
Miller NZ, Goldman GS.
Hum Exp Toxicol. 2011 Sep;30(9):1420-8.
pdf here
The infant mortality rate (IMR) is one of the most important indicators of the
socio-economic well-being and public health conditions of a country. The US
childhood immunization schedule specifies 26 vaccine doses for infants aged less
than 1 year--the most in the world--yet 33 nations have lower IMRs. Using linear
regression, the immunization schedules of these 34 nations were examined and a
correlation coefficient of r = 0.70 (p < 0.0001) was found between IMRs and the
number of vaccine doses routinely given to infants. Nations were also grouped
into five different vaccine dose ranges: 12-14, 15-17, 18-20, 21-23, and 24-26.
The mean IMRs of all nations within each group were then calculated. Linear
regression analysis of unweighted mean IMRs showed a high statistically
significant correlation between increasing number of vaccine doses and
increasing infant mortality rates, with r = 0.992 (p = 0.0009). Using the Tukey-Kramer
test, statistically significant differences in mean IMRs were found between
nations giving 12-14 vaccine doses and those giving 21-23, and 24-26 doses. A
closer inspection of correlations between vaccine doses, biochemical or
synergistic toxicity, and IMRs is essential.
see also:
A Positive Association
found between Autism Prevalence and Childhood Vaccination uptake across the U.S.
Population.
Delong G.
J Toxicol Environ Health A. 2011 Jan;74(14):903-16.
pdf here
The reason for the rapid rise of autism in the United States that began in the
1990s is a mystery. Although individuals probably have a genetic predisposition
to develop autism, researchers suspect that one or more environmental triggers
are also needed. One of those triggers might be the battery of vaccinations that
young children receive. Using regression analysis and controlling for family
income and ethnicity, the relationship between the proportion of children who
received the recommended vaccines by age 2 years and the prevalence of autism (AUT)
or speech or language impairment (SLI) in each U.S. state from 2001 and 2007 was
determined. A positive and statistically significant relationship was found: The
higher the proportion of children receiving recommended vaccinations, the higher
was the prevalence of AUT or SLI. A 1% increase in vaccination was associated
with an additional 680 children having AUT or SLI. Neither parental behavior nor
access to care affected the results, since vaccination proportions were not
significantly related (statistically) to any other disability or to the number
of pediatricians in a U.S. state. The results suggest that although mercury has
been removed from many vaccines, other culprits may link vaccines to autism.
Further study into the relationship between vaccines and autism is warranted.
Do aluminum vaccine
adjuvants contribute to the rising prevalence of autism?
Tomljenovic L,
Chris Shaw
J Inorg Biochem. 2011 Nov;105(11):1489-99. Epub 2011 Aug 23.
pdf here
Autism spectrum disorders (ASD) are serious multisystem developmental disorders
and an urgent global public health concern. Dysfunctional immunity and impaired
brain function are core deficits in ASD. Aluminum (Al), the most commonly used
vaccine adjuvant, is a demonstrated neurotoxin and a strong immune stimulator.
Hence, adjuvant Al has the potential to induce neuroimmune disorders. When
assessing adjuvant toxicity in children, two key points ought to be considered:
(i) children should not be viewed as "small adults" as their unique physiology
makes them much more vulnerable to toxic insults; and (ii) if exposure to Al
from only few vaccines can lead to cognitive impairment and autoimmunity in
adults, is it unreasonable to question whether the current pediatric schedules,
often containing 18 Al adjuvanted vaccines, are safe for children? By applying
Hill's criteria for establishing causality between exposure and outcome we
investigated whether exposure to Al from vaccines could be contributing to the
rise in ASD prevalence in the Western world. Our results show that: (i) children
from countries with the highest ASD prevalence appear to have the highest
exposure to Al from vaccines; (ii) the increase in exposure to Al adjuvants
significantly correlates with the increase in ASD prevalence in the United
States observed over the last two decades (Pearson r=0.92, p<0.0001); and (iii)
a significant correlation exists between the amounts of Al administered to
preschool children and the current prevalence of ASD in seven Western countries,
particularly at 3-4 months of age (Pearson r=0.89-0.94, p=0.0018-0.0248). The
application of the Hill's criteria to these data indicates that the correlation
between Al in vaccines and ASD may be causal. Because children represent a
fraction of the population most at risk for complications following exposure to
Al, a more rigorous evaluation of Al adjuvant safety seems warranted.